The effect of microwave irradiation on DNA hybridization.

نویسندگان

  • Wesleigh F Edwards
  • Douglas D Young
  • Alexander Deiters
چکیده

The effect of microwave irradiation on DNA/DNA hybridization has been studied under controlled power and temperature conditions. It was discovered that microwave irradiation led to the melting of double-stranded deoxyoligonucleotides well below their thermal melting temperature and independent of the length of the deoxyoligonucleotides. These observations indicate a specific interaction of microwaves with DNA, and have important implications in the chemical or enzymatic processing of DNA under microwave heating.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 7 12  شماره 

صفحات  -

تاریخ انتشار 2009